Many researchers are interested in nano-formulations for medicinal drugs. These nano-formulations improve the properties of traditional drugs and are specific for the delivery site. For enhanced drug formulation, some of the most popular nano-formulations in pharmaceutical industry include liposomes (polymeric nanoparticles), micelles, nano-emulsions, liposomes and nano-emulsions. There are many synthesis methods that can be used to prepare nano-formulations for drug delivery in the biological system. The size and shape, biochemical properties, and targeted site are all factors that influence the choice of synthesis method. This article will discuss recent advances in nano-formulation, and their progressive impact on the pharmaceutical industry and research. Also, the process challenges associated with consistent generation of nanoformulations for drug distribution are addressed.

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